Design, synthesis, and evaluation of indole-pyridine chalcone derivatives as novel HK2 inhibitors to modulate macrophage glycolysis and inflammation for IBD treatment

European Journal of Medicinal Chemistry 2026

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Authors: Yawei Han, Guangyuan Liu, Huimin Yuan, Yuhao Wei, Mingze Wu, Sijie Yin, Yunlong Liu, Liqun Gu, Jian Zhang, Xiaoshuang Wang, Yi Zhou, Ming Xiang
+1 more Mengzhu Zheng
DOI: 10.1016/j.ejmech.2026.118922
Cited by: 1
References: 30

Fields of Study & Subjects

Immune cells in cancer Cancer Hypoxia and Metabolism Protein Tyrosine Phosphatases

Publication details

Journal / source
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Volume
314
Pages
118922–118922
Publication date
5 May 2026
Language
EN