One destination, three routes: Tacrine-Celecoxib hybrids targeting cholinesterases, COX-2, and carbonic anhydrases in cognitive impairment linked to metabolic dysfunction

European Journal of Medicinal Chemistry 2026 Open access

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Authors: Nayera W. Hassan, Ola S Afifi, Maryam A.Z. El-Attar, Yasmine N. Kamel, Hend A. Yassin, Hanan Mohamed Nomeir, Andrea Angeli, Hala F. Labib, Manal A Elsheikh, Mariam Zewail, Evelyn M. Gerges, Ahmed F. El-Yazbi
+10 more Rosaria Spagnuolo, Marina Naldi, Mohamed I. Ashmawy, Waheed K. Zahra, Sherif F. Hammad, Claudiu T. Supuran, Manuela Bartolini, Perihan A. Elzahhar, Ahmed S. F. Belal, Shrouk M. Abd El Wahab
DOI: 10.1016/j.ejmech.2026.118984
Cited by: 1
References: 100

Fields of Study & Subjects

Cholinesterase and Neurodegenerative Diseases Enzyme function and inhibition Nicotinic Acetylcholine Receptors Study

Publication details

Journal / source
European Journal of Medicinal Chemistry
Publisher
Elsevier BV
Volume
315
Pages
118984–118984
Publication date
21 May 2026
Language
EN