Long-Term Outcomes of IgM-Positive Plasma Cell Tubulointerstitial Nephritis

Kidney International Reports 2026 Open access

Read full text
Authors: Naoki Takahashi, Haruyoshi Yoshida, Hideki Kimura, Chie Yamamoto, Makoto Yamamoto, Nanami Iwamura, K Matsuta, Sho Nishikawa, Kazuhisa Nishimori, Sachiko Fukushima, Yudai Nishikawa, Mamiko Kobayashi
+4 more Kenji Kasuno, Hironobu Naiki, Masayuki Iwano, Tadashi Toyama
DOI: 10.1016/j.ekir.2025.103764
Cited by: 2
References: 9

Abstract

IgM-positive plasma cell tubulointerstitial nephritis (IgMPC-TIN) is a rare immune-mediated kidney disease first described in 2017,1 characterized by dense IgM-producing plasma cell infiltration, distal renal tubular acidosis, Fanconi syndrome, and frequent coexistence with Sjögren’s syndrome and primary biliary cholangitis.

Fields of Study & Subjects

Nephrotoxicity and Medicinal Plants Renal Diseases and Glomerulopathies Sarcoidosis and Beryllium Toxicity Research

Publication details

Journal / source
Kidney International Reports
Publisher
Elsevier BV
Volume
11
Issue
3
Pages
103764–103764
Publication date
6 January 2026
Language
EN