Beyond Lymphocytic Inflammation: Immune Architecture as a Determinant of Renal Outcomes
Abstract
The study by Boudhabhay et al., published in Kidney International Reports, provides a timely and mechanistically oriented contribution to the evolving understanding of immune checkpoint inhibitor–associated acute interstitial nephritis (ICI-AIN).1 By integrating multiplex immunofluorescence with unsupervised clustering, the authors move beyond descriptive histology to propose biologically distinct inflammatory subtypes with prognostic relevance.
Fields of Study & Subjects
Cancer Immunotherapy and Biomarkers
Acute Kidney Injury Research
Renal Diseases and Glomerulopathies
Publication details
- Journal / source
- Kidney International Reports
- Volume
- 11
- Issue
- 5
- Pages
- 106386–106386
- Publication date
- 26 February 2026
- Language
- EN