Beyond Lymphocytic Inflammation: Immune Architecture as a Determinant of Renal Outcomes

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Authors: Kanishka Harariya, Thakur Rohit Singh, Ankita Kalra, Swarupanjali Padhi, Fayaz Ahamed
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References: 1

Abstract

The study by Boudhabhay et al., published in Kidney International Reports, provides a timely and mechanistically oriented contribution to the evolving understanding of immune checkpoint inhibitor–associated acute interstitial nephritis (ICI-AIN).1 By integrating multiplex immunofluorescence with unsupervised clustering, the authors move beyond descriptive histology to propose biologically distinct inflammatory subtypes with prognostic relevance.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Acute Kidney Injury Research Renal Diseases and Glomerulopathies

Publication details

Journal / source
Kidney International Reports
Volume
11
Issue
5
Pages
106386–106386
Publication date
26 February 2026
Language
EN