Refining AKI Diagnosis: Is There a Return on the Investment?
Abstract
Nearly 25 years of research have demonstrated the clear negative impact of acute kidney injury (AKI) both in acute and chronically ill patients. Data repeatedly demonstrates a dose-dependent relationship between AKI severity and mortality.1-3 What remains unclear, however, is if and when windows of therapeutic opportunity exist in the time course of AKI for a given patient. Though the gold standard for diagnosis remains change in serum creatinine, evidence strongly suggests prognosis of the AKI or the AKI associated patient sequelae is not possible based on SCr alone.
Fields of Study & Subjects
Acute Kidney Injury Research
Chronic Kidney Disease and Diabetes
Chemotherapy-induced organ toxicity mitigation
Publication details
- Journal / source
- Kidney International Reports
- Volume
- 11
- Issue
- 4
- Pages
- 106463–106463
- Publication date
- 5 March 2026
- Language
- EN