Randomized Trial of Dietary Nitrate Supplementation in CKD Pregnancy (ORCHARD-BEET)

Kidney International Reports 2026 Open access

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Authors: P. N. Smith, Danielle Ashworth, Rachel Hung, Yanzhong Wang, Andrew J. Webb, Kathryn Dalrymple, Katherine Clark, Lucy C. Chappell, Kate Wiles, Kate Bramham, P. N. Smith, Kate Bramham
+25 more Kate Wiles, Matthew Hall, Liz Lightstone, Philip Webster, Jenny Myers, Lucy Chappell, Laura McCabe, Jennifer Sparkes, Jorge Jesus-Silva, Alison Armitage, Laura Skinner, K. Bramham, P. Smith, L. C. Chappell, D. Ashworth, K. Clark, K. Dalrymple, A. Clery, C. Reid, L. MacKillop, E. Cottrell, D. Banerjee, F. McCarthy, M. Dodd, E. Wong
DOI: 10.1016/j.ekir.2026.106704
Cited by: 1
References: 32

Abstract

Introduction Nearly half of pregnant women with moderate-severe chronic kidney disease (CKD) will require dialysis or lose ≥25% kidney function by 12-months after delivery with high rates of neonatal complications. No targeted approaches have been developed to improve maternal outcomes. Methods Pregnant women with stage G2-G5 CKD (

Fields of Study & Subjects

Pregnancy and preeclampsia studies Pregnancy and Medication Impact Gestational Diabetes Research and Management

Publication details

Journal / source
Kidney International Reports
Publisher
Elsevier BV
Volume
11
Issue
10
Pages
106704–106704
Publication date
17 July 2026
Language
EN