Maternal pre-pregnancy body mass index, gestational weight gain and epilepsy in the offspring: A population-based cohort study

Epilepsy Research 2026 Open access

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Authors: Jiawen Chen, Haoran Zhuo, Tormod Rogne, Zeyan Liew
DOI: 10.1016/j.eplepsyres.2026.107760
Cited by: 0
References: 43

Abstract

OBJECTIVE: This study investigated whether maternal pre-pregnancy body mass index (BMI) and non-optimal gestational weight gain (GWG) are associated with epilepsy in the offspring. DESIGN, SETTING, POPULATION: We studied 3,816,438 children born between 2007 and 2015 ascertained from the California birth records. MAIN OUTCOME MEASURES: Childhood epilepsy was ascertained using the diagnostic records from the California's Department of Developmental Services. METHODS: ) and non-optimal GWG (kg), adjusting for confounders. We compared maternal pre-pregnancy overweight (25 ≤ BMI

Fields of Study & Subjects

Gestational Diabetes Research and Management Birth Development and Health Pharmacological Effects and Toxicity Studies

Publication details

Journal / source
Epilepsy Research
Volume
222
Pages
107760–107760
Publication date
17 February 2026
Language
EN