Association between cumulative glucocorticoid exposure and epicardial adipose tissue volume in systemic lupus erythematosus

EULAR Rheumatology Open 2026 Open access

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Authors: Lévi-Dan Azoulay, Nadjia Kachenoura, Samia Boussouar, Etienne Charpentier, Nassim Ait Abdallah, Micheline Pha, Miguel Hie, Alexis Mathian, Fleur Cohen Aubart, Julien Haroche, Zahir Amoura, Alban B. Redheuil
DOI: 10.1016/j.ero.2025.12.009
Cited by: 0
References: 3

Abstract

During the past decade, epicardial adipose tissue (EAT) volume has emerged as a promising cardiovascular risk biomarker both in the general population and in systemic lupus erythematosus (SLE) [1,2]. In 2012, Lipson et al [3] reported that patients with SLE had increased EAT volumes when compared with matched controls. In their study, EAT volume was independently associated with triglycerides and cumulative glucocorticoid (GC) exposure, although disease activity and damage indices were not considered [3].

Fields of Study & Subjects

Systemic Lupus Erythematosus Research Cardiovascular Disease and Adiposity Cardiovascular Function and Risk Factors

Publication details

Journal / source
EULAR Rheumatology Open
Volume
2
Issue
1
Pages
108–110
Publication date
12 January 2026
Language
EN