200P Molecular landscape of radiation-induced sarcomas: Evidence from a systematic review

ESMO rare cancers. 2026 Open access

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Authors: Jens Jakob, Melissa Harbrücker, L Raster, C. Krug, M-V. Teleanu, Madelaine Hettler, C. Reissfelder, B. Kasper, P. Hohenberger, Stefan Fröhling
DOI: 10.1016/j.esmorc.2026.100406
Cited by: 0

Abstract

Radiation-induced sarcomas (RIS) are rare second malignancies occurring after radiotherapy for a primary cancer. Their molecular landscape may prove to be useful to distinguish them from sporadic sarcomas or provide novel therapeutic approaches. This review compiles the available molecular data on RIS.

Fields of Study & Subjects

Multiple and Secondary Primary Cancers Sarcoma Diagnosis and Treatment Vascular Tumors and Angiosarcomas

Publication details

Journal / source
ESMO rare cancers.
Volume
5
Pages
100406–100406
Publication date
1 March 2026
Language
EN