234eP Modeling the predictive and prognostic potential of biomarker-based personalized approaches in soft tissue sarcomas
Abstract
Soft tissue sarcomas (STS) are rare malignant neoplasms of mesenchymal origin characterized by high molecular heterogeneity. Variability in clinical outcomes is frequently associated with underlying genetic and epigenetic alterations. Evidence suggests that biomarkers such as RRM1, MGMT, TUBB3, and PTEN may play a significant role in predicting chemotherapy response as well as assessing survival outcomes. The aim of this study was to evaluate the clinicopathological significance of these biomarkers and to determine their potential prognostic and predictive value.
Fields of Study & Subjects
Sarcoma Diagnosis and Treatment
Chromatin Remodeling and Cancer
Breast Cancer Treatment Studies
Publication details
- Journal / source
- ESMO rare cancers.
- Volume
- 5
- Pages
- 100440–100440
- Publication date
- 1 March 2026
- Language
- EN