Bladder paraganglioma with lymph node metastasis treated by surgery with long-term recurrence-free survival: A case report

We report a rare case of bladder paraganglioma with lymph node metastasis. A 51-year-old man presented with gross hematuria caused by a bladder tumor. During transurethral resection, a sudden hypertensive crisis occurred, raising suspicion of a catecholamine-producing tumor. Pathological analysis confirmed bladder paraganglioma. Partial cystectomy combined with left pelvic lymph node dissection was performed because preoperative computed tomography showed mild swelling of the left obturator lymph node. At the time of writing, the patient has remained disease-free for 5 years. This case suggests that complete surgical resection may achieve long-term recurrence-free survival even in patients with localized lymph node metastasis. • ・Bladder paraganglioma with lymph node metastasis is rare and difficult to diagnose preoperatively. • ・Complete surgical resection may achieve long-term recurrence-free survival even in patients with localized lymph node metastasis. • ・Continuous and vigilant follow-up is essential because of the unpredictable biological behavior and potential for late recurrence.