Dynapenic–metabolic obesity and incident stroke in middle-aged and older adults: The mediating role of intrinsic capacity and systemic inflammation

Experimental Gerontology 2026 Open access

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Authors: Yang Dong, Bo Yang
DOI: 10.1016/j.exger.2026.113143
Cited by: 1

Abstract

Conventional obesity definitions overlook heterogeneity related to metabolic health and muscle strength. This study examined the associations between dynapenic–metabolic obesity (DMO) and incident stroke among middle-aged and older Chinese adults. Our study included 11,770 participants aged ≥45 years from the China Health and Retirement Longitudinal Study (CHARLS, 2011–2018) with 2011 as baseline. Dynapenia was defined by handgrip strength (

Fields of Study & Subjects

Adipokines Inflammation and Metabolic Diseases Nutrition and Health in Aging Diabetes Cardiovascular Risks and Lipoproteins

Publication details

Journal / source
Experimental Gerontology
Publisher
Elsevier BV
Pages
113143–113143
Publication date
1 April 2026
Language
EN