Walnut glutelin antibacterial peptides target Staphylococcus aureus through metabolic pathway and novel antibacterial peptides identification

Food Chemistry X 2026 Open access

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Authors: Hui Ma, Zhiqiang Lu, Han Yang, Yansong Gao, Songyi Lin, Fang Li, Lingming Kong
DOI: 10.1016/j.fochx.2026.103698
Cited by: 2
References: 41

Abstract

To address challenges from biofilm-forming, antibiotic-resistant pathogens like Staphylococcus aureus, this study explored walnut glutelin antibacterial peptides (WGAP) as sustainable alternatives, integrating metabolomics, peptidomics, and computational biology to uncover their mechanisms and identify novel antibacterial peptides. WGAP exhibited significant efficacy against Staphylococcus aureus (MIC = 53.5 μg/mL) with minimal hemolysis (

Fields of Study & Subjects

Protein Hydrolysis and Bioactive Peptides Food Allergy and Anaphylaxis Research Bee Products Chemical Analysis

Publication details

Journal / source
Food Chemistry X
Publisher
Elsevier BV
Volume
34
Pages
103698–103698
Publication date
1 February 2026
Language
EN