CDDO-Me alleviates doxorubicin/lapatinib-induced cardiotoxicity by activating the NRF2/GPX4 axis to inhibit oxidative stress and ferroptosis

Free Radical Biology and Medicine 2026

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Authors: Xiaojiao Chen, Bo Chen, Qinghua Hu, Lifei Suo, Manjialan Yin, Manjialan Yin, Zengyi Huang, Guangxu Huang, Zengyi Huang, Yan-Wei Yin, Weiying Zhou
DOI: 10.1016/j.freeradbiomed.2026.03.068
Cited by: 2
References: 45

Fields of Study & Subjects

Ferroptosis and cancer prognosis Chemotherapy-induced cardiotoxicity and mitigation Cancer Lipids and Metabolism

Publication details

Journal / source
Free Radical Biology and Medicine
Publisher
Elsevier BV
Volume
250
Pages
468–482
Publication date
31 March 2026
Language
EN