Corrigendum. Guía de práctica clínica multidisciplinar de manejo de la esteatosis hepática metabólica

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Authors: Manuel Romero-Gómez, Javier Escalada, Mar Noguerol, Antonio Pérez, Juana Carretero, Javier Crespo, Juan J Mascort, Ignacio Aguilar, Francisco Tinahones, Pedro Cañones, Ricardo Gómez-Huelgas, Daniel Antonio de Luis
+4 more Idoia Genúa Trullos, R. Aller, Miguel A. Rubio, José Luis Calleja
Cited by: 1
References: 136

Abstract

Metabolic hepatic steatosis (MetHS) is a clinically heterogeneous, multisystemic, dynamic, and complex disease, whose progression is one of the main causes of cirrhosis and hepatocarcinoma. This clinical practice guideline aims to respond to its main challenges, both in terms of disease burden and complexity. To this end, recommendations have been proposed to experts through the Delphi method. The consensus was optimal in recommendations regarding type 2 diabetes as a risk factor (1.5.1, 4.5.1), in which cases early detection of MetHS should be carried out (4.5.2). Its results also emphasize the importance of the use of non-invasive tests (FIB-4, NFS, HFS) for the exclusion of significant fibrosis in patients with suspected MetHS (2.3.1, 2.3.3). Diagnosis should be carried out through the sequential combination of non-invasive indices and transient elastography by FibroScan® for its risk stratification (2.3.3). A nearly unanimous consensus was reached regarding the role of early prevention in the impact on the quality of life and survival of patients (5.1.2), as well as on the effectiveness of the Mediterranean diet and physical exercise in relation to the improvement of steatosis, steatohepatitis and fibrosis in MetHS patients (5.2.2) and on the positive results offered by resmiterom and semaglutide in promoting fibrosis regression (5.4.1). Finally, a great consensus has been reached regarding the importance of multidisciplinary management in MetHS, for which it is essential to agree on multidisciplinary protocols for referral between levels in each health area (6.2.1), as well as ensuring that referrals to Hepatology/Digestive and Endocrinology or Internal Medicine services are effective and beneficial to prevent the risk of disease progression (6.2.3, 6.3.1).

Fields of Study & Subjects

Liver Disease Diagnosis and Treatment Health and Lifestyle Studies Diet Metabolism and Disease

Publication details

Journal / source
Gastroenterología y Hepatología
Publisher
Elsevier BV
Volume
49
Issue
5
Pages
502639–502639
Publication date
22 January 2026
Language
ES