P090: Precision genomics in myeloid malignancies: Insights from combined sequencing and cytogenetic profiling at UVA

Genetics in Medicine Open 2026 Open access

Read full text
Authors: Aline Rangel Pozzo, Gabriela Guardia, Vanessa L. Smith, Eli S. Williams, Jinbo Fan
DOI: 10.1016/j.gimo.2026.103581
Cited by: 0

Abstract

Myeloid malignancies are characterized by a diverse spectrum of somatic genetic alterations, with variant patterns influenced by patient age, sex, and disease subtype. The integration of next-generation sequencing (NGS) into routine diagnostics has transformed molecular characterization, enabling the detection of recurrent variants and structural abnormalities that support disease classification and risk stratification.

Fields of Study & Subjects

Acute Myeloid Leukemia Research Cancer Genomics and Diagnostics Chronic Myeloid Leukemia Treatments

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
103581–103581
Publication date
1 January 2026
Language
EN