P093: AML patients with leukemia cutis transformation showed similar cytogenetics and genomics profiles
Abstract
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by clonal expansion, uncontrolled proliferation, and differentiation arrest of myeloid progenitor cells. Leukemia cutis is characterized by the presence of neoplastic leukocytes infiltrating the skin. KMT2A rearrangements are present in about 10% of AML cases across various age groups, indicating that they represent unique, genetically defined subtypes of AML.
Fields of Study & Subjects
Acute Myeloid Leukemia Research
Retinoids in leukemia and cellular processes
Chromatin Remodeling and Cancer
Publication details
- Journal / source
- Genetics in Medicine Open
- Volume
- 4
- Pages
- 103584–103584
- Publication date
- 1 January 2026
- Language
- EN