P443: Poor oral health significantly increases the likelihood of heart disease: Evidence from Mendelian randomization using genomic structural equation modeling
Abstract
The association between oral health and systemic health is well-documented and thought to occur through pathways initiated by pathogenic infection, systemic inflammation, and/or disturbances of the immune system. Recently, studies have attempted to better understand the relationship between heart disease and oral health. Previous associational studies have identified inflammation from periodontitis as a contributor to heart disease, and a systematic review and metanalysis found that periodontitis increases the risk of heart disease independent of other known risk factors.
Fields of Study & Subjects
Oral microbiology and periodontitis research
Genetic Associations and Epidemiology
Dental Health and Care Utilization
Publication details
- Journal / source
- Genetics in Medicine Open
- Volume
- 4
- Pages
- 103935–103935
- Publication date
- 1 January 2026
- Language
- EN