P507: Assessing Alzheimer's disease risk perception and attitudes in asymptomatic high-risk individuals enrolled in a multimodal lifestyle intervention trial

Genetics in Medicine Open 2026 Open access

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Authors: J. Nicholas Cochran, Tanner Coleman, Jada Pugh, Whitley V. Kelley, Anna Hurst, Jessica Chasteen, Mary Jones, Elizabeth Dunne, Leroy Hood, Jennifer C. Lovejoy, Nicholas Cochran
DOI: 10.1016/j.gimo.2026.103999
Cited by: 0

Abstract

Alzheimer’s disease (AD) represents an ever-growing clinical and public health burden and create significant hardship for affected individuals and caregivers. Critically, recent therapeutic advancements indicate that greater disease modulation occurs with earlier intervention. Additionally, recent trials demonstrate that multimodal lifestyle interventions may significantly delay the onset of Alzheimer’s in individuals with mild cognitive impairment (MCI). It therefore stands to reason that lifestyle interventions, when applied in an asymptomatic, high-risk population, could substantially alter the risk of disease.

Fields of Study & Subjects

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Ethics in Clinical Research

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
103999–103999
Publication date
1 January 2026
Language
EN