P659: Improving hereditary cancer risk assessment: Systematic reanalysis supports multigene cancer predisposition panel over single cancer panel

Genetics in Medicine Open 2026 Open access

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Authors: Yinghong Pan, Patrick D. Danley, Evan Powell, Gregory Humphreys, Adalena V. Nanni, Marianne McGuire, Tamar Kramer, Phuong Mai, Alexander N. Yatsenko, Daniel B. Bellissimo, Fen Guo
DOI: 10.1016/j.gimo.2026.104149
Cited by: 0

Abstract

Genetic diagnosis for patients with hereditary cancer is imperative and has become standard clinical practice. Next-generation sequencing (NGS) enables the simultaneous sequencing of a considerable number of hereditary cancer predisposition genes efficiently.

Fields of Study & Subjects

BRCA gene mutations in cancer Genomics and Rare Diseases Genetic factors in colorectal cancer

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
104149–104149
Publication date
1 January 2026
Language
EN