P685: From gene sequence to phenotype: Clinical implications of a variant in SCN5A in Brugada syndrome: A case report

Genetics in Medicine Open 2026 Open access

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Authors: Yasmin de Sá Ortiz, Isabella Bettega Queiroz, Heloisa Stadler Ribas, Márcio Rogério Ortiz, Niraj Mehta, Maria Pinheiro Távora, Adriano Senter Magajevski, Salmo Raskin, Liya Regina Mikami
DOI: 10.1016/j.gimo.2026.104175
Cited by: 0

Abstract

The patient was classified as compatible with BrS; however, the syncope was suggestive of vasovagal syncope. Therefore, the patient doesn’t meet the criteria for implantation of an implantable cardioverter-defibrillator (ICD), so implantation of a loop recorder for prolonged monitoring was suggested due to the history of syncope.

Fields of Study & Subjects

Cardiac electrophysiology and arrhythmias Ion channel regulation and function Cardiovascular Syncope and Autonomic Disorders

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
104175–104175
Publication date
1 January 2026
Language
EN