P726: DNA and decisions: The interface between genetic testing and termination for congenital anomalies

Genetics in Medicine Open 2026 Open access

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Authors: Haley M. Crane, Renee Wright, Alexandria Budney, Katie Gianforcaro, Gustavo Eisenberg, Paige McDunnah, Juliana S. Gebb, Shelly Soni, Joanna Cole, Nahla Khalek
DOI: 10.1016/j.gimo.2026.104218
Cited by: 0

Abstract

Although 20-30% of fetuses and neonates with congenital anomalies have an identifiable genetic etiology, the decision to pursue prenatal diagnosis is nuanced. Genetic testing performed via chorionic villus sampling or amniocentesis can also be accomplished on products of conception. We aim to examine the clinical utility and yield of prenatal and postmortem genetic testing coordinated by a single fetal center for anomalous pregnancies that were terminated.

Fields of Study & Subjects

Prenatal Screening and Diagnostics Genomics and Rare Diseases Congenital Anomalies and Fetal Surgery

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
104218–104218
Publication date
1 January 2026
Language
EN