P732: Parental health implications identified through prenatal sequencing for fetal anomalies

Genetics in Medicine Open 2026 Open access

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Authors: Carmen M. A. Santoli, Billie Rachael Lianoglou, Nuriye Sahin‐Hodoglugil, Katie Tick, Rozlyn C. T. Boutin, Kate Swanson, Patrick Devine, Jessica Van Ziffle, Mary E. Norton, Teresa N. Sparks
DOI: 10.1016/j.gimo.2026.104224
Cited by: 0

Abstract

While the primary goal of prenatal genomic sequencing is to identify fetal disease, this testing can also uncover health implications for biological parents. Fetal exome and genome sequencing often incorporate parental samples to aid with variant interpretation, and as a result, information may be learned about parental health when genetic variants are inherited. We aimed to determine the frequency with which genetic variants with potential parental health implications were identified through genomic sequencing for fetal congenital anomalies.

Fields of Study & Subjects

Prenatal Screening and Diagnostics Genomics and Rare Diseases Medical and Health Sciences Research

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
104224–104224
Publication date
1 January 2026
Language
EN