P750: Association between preimplantation genetic testing, serum aneuploidy screening and pregnancy outcomes

Genetics in Medicine Open 2026 Open access

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Authors: Karina Quan, Suha J. Patel, William Goh, Noa Brenner, Marissa Miyagi, Megan Goh, Hyeong Jun Ahn, Jingwen Hou, Robert B. Hufnagel
DOI: 10.1016/j.gimo.2026.104242
Cited by: 0

Abstract

Preimplantation genetic testing (PGT) improves in vitro fertilization (IVF) success rates and is performed on the developing trophectoderm. Due to the possibility of mosaicism, the American College of Obstetricians and Gynecologists recommends offering genetic screening or testing to patients who underwent IVF and PGT. We hypothesized that PGT may alter placental serum analytes, resulting in positive screening results and also an increase in adverse pregnancy outcomes.

Fields of Study & Subjects

Prenatal Screening and Diagnostics Assisted Reproductive Technology and Twin Pregnancy Reproductive Health and Technologies

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
104242–104242
Publication date
1 January 2026
Language
EN