P546: The Genomics-enabled Learning Health Systems (gLHS) Network: Selection of projects to increase adoption of genomic medicine practices in health systems

Genetics in Medicine Open 2026 Open access

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Authors: Megan He, Caitlin G. Allen, Carolyn Marie Audet, Rinad S. Beidas, Alexander G. Bick, Adam Buchanan, Andrea N. Burnett‐Hartman, Paul Richard Dexter, Patricia Franklin, Cheryl L. Gatto, Lucy A. Godley, Kensaku Kawamoto
+18 more Sunil B. Kripalani, Alanna Kulchak Rahm, Jodell E. Linder, Cara Zayac McCormick, Elizabeth M. McNally, Mollie A. Minear, Ana Morales, Gila I. Neta, Lori A. Orlando, Josh Peterson, Dan M. Roden, Maren Theresa Scheuner, Todd C. Skaar, Martin Tristani‐Firouzi, Jason L. Vassy, Deepak Voora, Mark D. Yandell, Miranda L. G. Hallquist
DOI: 10.1016/j.gimo.2026.104364
Cited by: 0

Abstract

The translation of genomic discovery to clinical practice has yet to reach its full potential in guiding healthcare decisions and improving health outcomes. Barriers include the limited scope of previous implementation efforts, lack of interoperability of genomic data, limited clinician familiarity with genetic testing protocols, and non-scalable approaches to returning genetic data. The Genomics-enabled Learning Health System (gLHS) Network, composed of six clinical sites, nine community partners, and a Coordinating Center (CC), was funded by the National Institutes of Health (NIH) in September 2024 to address these issues.

Fields of Study & Subjects

Genomics and Rare Diseases Artificial Intelligence in Healthcare and Education Electronic Health Records Systems

Publication details

Journal / source
Genetics in Medicine Open
Volume
4
Pages
104364–104364
Publication date
1 January 2026
Language
EN