Severe leukemoid reaction and spontaneous tumor lysis syndrome in a young patient with undifferentiated Lynch syndrome-associated ovarian cancer

Gynecologic Oncology Reports 2026 Open access

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Authors: Claudia Marie Watkins, Mojtaba Allahifard, Juan Adolfo Cattoni, Lauren Montemorano
DOI: 10.1016/j.gore.2026.102026
Cited by: 0
References: 8

Abstract

•Lynch syndrome-associated ovarian cancer can present at a young age and be of high-grade histology.•Spontaneous tumor lysis syndrome can occur in ovarian cancer and may be the initial presentation.•Severe leukemoid reaction can occur as a paraneoplastic phenomenon in ovarian cancer and may portend a poor prognosis.•Leukemoid reaction and tumor lysis syndrome occurring together in ovarian cancer may signal aggressive tumor biology.

Fields of Study & Subjects

Methemoglobinemia and Tumor Lysis Syndrome Chemotherapy-related skin toxicity Acute Lymphoblastic Leukemia research

Publication details

Journal / source
Gynecologic Oncology Reports
Volume
63
Pages
102026–102026
Publication date
7 January 2026
Language
EN