Significant brain atrophy following new-onset refractory status epilepticus: A rare case of COVID-19 encephalitis

Heliyon 2026 Open access

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Authors: Yongxing Chen, Pingping Liu, Huiwen Luan, Hui Zhang, Yueqi Zhang
DOI: 10.1016/j.heliyon.2026.e44603
Cited by: 0
References: 11

Abstract

The novel coronavirus (SARS-CoV-2) is a highly infectious respiratory virus with significant pathogenicity. Although its impact has lessened in many countries, its ongoing mutations and sporadic outbreaks remain a public health concern. Notably, some cases present severe neurological manifestations. Herein, we report a patient who developed new-onset refractory status epilepticus (NORSE) and significant brain atrophy following SARS-CoV-2 infection.

Fields of Study & Subjects

Long-Term Effects of COVID-19 Infectious Encephalopathies and Encephalitis Epilepsy research and treatment

Publication details

Journal / source
Heliyon
Volume
12
Issue
3
Pages
e44603–e44603
Publication date
16 February 2026
Language
EN