Impact of Sex Differences on Long-Term Survival Following TAVI in Patients With Aortic Stenosis: Insights From the TAVI-NOR Study
Abstract
BACKGROUND: The incidence of aortic stenosis (AS) in the older adult population in Western countries is increasing. When left untreated, AS progresses to clinical heart failure, reduced quality of life and functional capacity, and ultimately death. We aimed to assess sex differences in the long-term survival benefits of transcatheter aortic valve implantation (TAVI) in patients with severe AS. METHOD: A total of 600 consecutive patients with AS who underwent TAVI were included. Clinical and echocardiographic data were analysed. Propensity score matching was performed to assess the impact of sex on the survival benefit following TAVI, yielding 213 men and women with similar baseline characteristics. RESULTS: The mean age in the total population was 80.8±6.5 years. Women (49.3%) were older (82.2±5.3 vs 79.5±7.3 years; p
Fields of Study & Subjects
Cardiac Valve Diseases and Treatments
Aortic Disease and Treatment Approaches
Pulmonary Hypertension Research and Treatments
Publication details
- Journal / source
- Heart Lung and Circulation
- Publisher
- Elsevier BV
- Volume
- 35
- Issue
- 5
- Pages
- 636–649
- Publication date
- 21 April 2026
- Language
- EN