Takotsubo syndrome complicated by dynamic left ventricular outflow tract obstruction after left bundle branch area pacing

HeartRhythm Case Reports 2026 Open access

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Authors: Paolo Pastori, Fabrizio De Rosa, Francesco Vitali, Andrea Botti, Giovanni Tortorella, Matteo Bertini
DOI: 10.1016/j.hrcr.2026.03.017
Cited by: 2
References: 7

Abstract

Left bundle branch area pacing (LBBAP) has emerged as a physiologic pacing strategy that better preserves ventricular synchrony compared with traditional right ventricular pacing (RVP).1,2 By engaging the native conduction system, LBBAP is associated with narrower QRS duration and improved hemodynamic performance.3,4 Although generally safe, the transseptal lead approach carries procedure-specific risks,5-7 including septal injury, coronary trauma, and rare stress-related cardiomyopathy. Takotsubo syndrome (TTS) has been reported after pacemaker implantation,8 including LBBAP.

Fields of Study & Subjects

Takotsubo Cardiomyopathy and Associated Phenomena Cardiac pacing and defibrillation studies Cardiac Structural Anomalies and Repair

Publication details

Journal / source
HeartRhythm Case Reports
Publisher
Elsevier BV
Volume
12
Issue
7
Pages
727–733
Publication date
25 March 2026
Language
EN