Peak QRS/T ratio and the spatial ventricular gradient differentiate acute vs chronic left bundle branch block after transcatheter aortic valve replacement

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Authors: Jonathan W. Waks, Marie‐France Poulin, Patricia Tung, Hans Friedrich Stabenau, Alice A. Haouzi, John-Ross D. Clarke, PETER J. ZIMETBAUM, Andre d'Avila, Beatie Ultimo, Kimberly A. Guibone, Katherine Kiernan, Alexandra Medline
+7 more Nicholas Simon Peters, Arunashis Sau, Fu Siong Ng, Daniel Bruce Kramer, Alexei V. Shvilkin, Roger J. Laham, Alfred E. Buxton
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References: 15

Abstract

Background: Differentiating chronic from acute left bundle branch block (LBBB) is useful in various cardiac disorders. Peak QRS/T ratio, a measure of cardiac memory, can differentiate chronic from acute LBBB with high sensitivity and specificity, but its utility in post-transcatheter aortic valve replacement (TAVR) patients with LBBB is unclear. Objective: This study aimed to validate the QRS/T ratio for differentiating chronic/acute LBBB in post-TAVR patients and assess whether the spatial ventricular gradient (SVG), which integrates 3-dimensional depolarization/repolarization throughout the cardiac cycle, could also distinguish chronic from acute LBBB. Methods: This was a post hoc analysis of a prospective, observational, single-center TAVR study. After TAVR, patients were classified as acute (new

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Cardiac electrophysiology and arrhythmias Cardiac pacing and defibrillation studies

Publication details

Journal / source
Heart Rhythm O2
Volume
7
Issue
5
Pages
928–937
Publication date
29 January 2026
Language
EN