Zero-contrast cardiac resynchronization therapy device implantation in heart failure patients with renal impairment

Heart Rhythm O2 2026 Open access

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Authors: Biagio Sassone, Marco Zuin, Angelo Melpignano, Martina De Raffele, Francesca Tiberia, Michele Malagù, Santo Virzì, Francesco Vitali, Cristina Balla, Enrico Bertagnin, Matteo Bertini
DOI: 10.1016/j.hroo.2026.02.026
Cited by: 0
References: 25

Abstract

BACKGROUND Coronary sinus (CS) venography is commonly used during cardiac resynchronization therapy (CRT) to guide left ventricular lead placement; however, iodinated contrast poses a substantial risk of contrast-induced acute kidney injury (CI-AKI) in patients with chronic kidney disease (CKD). Evidence supporting contrast-sparing CRT techniques remains limited. OBJECTIVE To assess the feasibility, safety, and renal outcomes of a zero-contrast CRT implantation strategy in CKD patients. METHODS Consecutive CKD patients (estimated glomerular filtration rate [eGFR]

Fields of Study & Subjects

Cardiac pacing and defibrillation studies Acute Kidney Injury Research Coronary Interventions and Diagnostics

Publication details

Journal / source
Heart Rhythm O2
Volume
7
Issue
6
Pages
1105–1113
Publication date
7 March 2026
Language
EN