An integrative multi-omics analysis leveraging Mendelian randomization and subsequent experimental validation prioritizes glutathione S-transferase mu 5 (GSTM5) as a genomic stability-related gene and a therapeutic vulnerability to PLK1 inhibition in breast cancer

International Journal of Biological Macromolecules 2026

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Authors: He Ma, Tiankang Li, Runcheng Huang, Yaping Liu, Lei Zhao, Zhigang Zhuang

DOI: 10.1016/j.ijbiomac.2026.151211

Cited by: 0

References: 40

Fields of Study & Subjects

Glutathione Transferases and Polymorphisms Cancer Genomics and Diagnostics Epigenetics and DNA Methylation

References 40