Tumor-like scalp lesions in a patient with ocular syphilis

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Authors: Hiroo Matsuo, Tomomi Fujii, So Goto, Satoshi Kutsuna
Cited by: 0
References: 6

Abstract

A 50-year-old man, with no prior history of sexually transmitted infections and negative screening for HIV, HBV, HCV, gonorrhea, and chlamydia, presented with progressive visual loss and was diagnosed with syphilitic retinitis [1]. Systemic examination revealed no rash on the trunk, palms, soles, oral mucosa, or genitalia. Two painless tumor-like nodular lesions on the scalp—firm, hyperpigmented, and dome-shaped (Figure 1A) —were initially presumed to be keloids; however, other differential diagnoses, including adnexal tumors, cutaneous lymphoma, and sarcoidosis, were also considered, and the lesions had been scheduled for surgical excision at another facility.

Fields of Study & Subjects

Syphilis Diagnosis and Treatment Fungal Infections and Studies Dermatology and Skin Diseases

Publication details

Journal / source
International Journal of Infectious Diseases
Volume
164
Pages
108410–108410
Publication date
19 January 2026
Language
EN