Disseminated Mycobacterium avium: A multi-organ system investigation

International Journal of Infectious Diseases 2026 Open access

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Authors: Christoffel Johannes Opperman, Sarishna Singh, Y. Ghebrekristos, Michael A. Linström, Lourens Jacobsz, Wynand J. Goosen
DOI: 10.1016/j.ijid.2026.108475
Cited by: 0
References: 4

Abstract

A 33-year-old HIV positive (CD4+T-cells =1cells/µl) patient, presented with a three-week history of non-dysentery, pancytopenia, and a urine lipoarabinomannan assay (urine‐LAM) positive. Abdominal ultrasound showed splenomegaly with diffuse hyperechoic nodules. Subsequently, Mycobacterium avium was cultured from blood, bone marrow aspirate, and repeatedly on sputum. Acid-fast bacilli were observed on stool microscopy and bone marrow biopsy (Figure 1). The patient died despite receiving treatment for M.

Fields of Study & Subjects

Mycobacterium research and diagnosis Infectious Diseases and Tuberculosis Actinomycetales infections and treatment

Publication details

Journal / source
International Journal of Infectious Diseases
Volume
165
Pages
108475–108475
Publication date
8 February 2026
Language
EN