Community-acquired pneumonia outside the intensive care unit: Clinical characteristics and impact of rapid molecular diagnostics in the Italian SIS-NET study

International Journal of Infectious Diseases 2026 Open access

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Authors: Luca Pipitò, Ilenia Giacchino, Chiara Vincenza Mazzola, Emanuele Nicastri, Teresa Fasciana, Massimo Puoti, Vincenzo Malagnino, Marco Iannetta, Delia Goletti, Maria Grazia Bocci, Antonella Minutolo, Clementina Cocuzza
+19 more Marco Merli, Prezioso Carla, Matteo Velardo, Maria Campione, Michael Damiano, Michele Spinicci, Bruno Tassone, Sandro Grelli, Marco Falcone, Laura Rindi, Alessandro Russo, Angela Quirino, Lorenzo Zammarchi, Dolores Limongi, Gian María Rossolini, Loredana Sarmati, Giovanni M. Giammanco, Antonino Giarratano, Antonio Cascio
DOI: 10.1016/j.ijid.2026.108988
Cited by: 1
References: 15

Abstract

OBJECTIVES: To describe the clinical, radiological, and microbiological characteristics of community-acquired pneumonia (CAP) managed outside the ICU and evaluate the impact of rapid microbiological diagnostics on hospital outcomes in a multicenter Italian cohort. METHODS: In this prospective observational study conducted across seven Italian centers (October 2024-October 2025), 176 adults hospitalized with CAP outside the ICU and a PaO₂/FiO₂ ratio

Fields of Study & Subjects

Pneumonia and Respiratory Infections Nosocomial Infections in ICU Respiratory viral infections research

Publication details

Journal / source
International Journal of Infectious Diseases
Publisher
Elsevier BV
Volume
171
Pages
108988–108988
Publication date
17 July 2026
Language
EN