Antimicrobial activity of native Lactobacillus cell-free supernatant against diarrheagenic Escherichia coli isolated from hospitalized patients in northern Iran

Indian Journal of Medical Microbiology 2026 Open access

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Authors: Farzaneh Rafie Sedaghat, Ali Mojtahedi, Meysam Hasannejad-Bibalan, Tofigh Yaghubi Kalurazi, Tohid Samadpour Zahmat-dar
DOI: 10.1016/j.ijmmb.2026.101063
Cited by: 1
References: 21

Abstract

BACKGROUND AND AIMS: Antibiotic resistance is a growing concern in the fight against Escherichia coli, a pathogen that causes various intestinal diseases. The present study explores the antibacterial effect of lactobacillus on E. coli pathotypes. METHODS: Inpatients stool samples were collected and E. coli pathotypes were identified. The antibacterial effect of five Lactobacillus on the pathotypes was investigated by broth microdilution and well diffusion methods. RESULTS: The CFS of L. plantarum, L. rueteri and L. acidophilus had the greatest antibacterial effect. CONCLUSION: Postbiotics have shown significant bactericidal effects against E. coli pathotypes. Their bactericidal effect can prevent the colonization of these pathotypes in hospitalized patients.

Fields of Study & Subjects

Probiotics and Fermented Foods Gut microbiota and health Infant Nutrition and Health

Publication details

Journal / source
Indian Journal of Medical Microbiology
Publisher
Elsevier BV
Volume
60
Pages
101063–101063
Publication date
20 January 2026
Language
EN