Quality-by-Design (QbD) optimization of lyophilization parameters for siRNA-loaded LNPs using sequential Design of Experiments (DoE)

International Journal of Pharmaceutics 2026 Open access

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Authors: Manon Degey, Laura Meloni, Berfin Dede, Inês Guerreiro, Noémie Penoy, Pierre‐Yves Sacré, Manon Berger, Louise Conrard, Erika Hendrickx, Erik Maquoi, Jeanne Leblond Chain, Brigitte Évrard
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DOI: 10.1016/j.ijpharm.2026.127032
Cited by: 1
References: 54

Fields of Study & Subjects

RNA Interference and Gene Delivery Protein purification and stability Nanoparticle-Based Drug Delivery

Publication details

Journal / source
International Journal of Pharmaceutics
Publisher
Elsevier BV
Volume
700
Pages
127032–127032
Publication date
2 June 2026
Language
EN