Formulation of amorphous solid dispersion of clofazimine, an extremely water-insoluble basic drug, via hot-melt extrusion by applying acid-base supersolubilization principle

International Journal of Pharmaceutics 2026

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Authors: Mufaddal H. Kathawala, Hari P Kandagatla, Alex Avdeef, Martin Kuentz, Tatjana Ž. Verbić, Abu T.M. Serajuddin

DOI: 10.1016/j.ijpharm.2026.127063

Cited by: 1

References: 42

Fields of Study & Subjects

Drug Solubulity and Delivery Systems Crystallography and molecular interactions Crystallization and Solubility Studies

References 42