Deficiency of Werner RecQ-type DNA helicase causes premature malnutrition in zebrafish

iScience 2026 Open access

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Authors: Kota Ujibe, Makoto Kashima, Miku Kataoka, Rintaro Shimada, Masashige Okamoto, Isao Kobayashi, Seiji Wada, Hiroki Matsuda, Akira Sakamoto, Hiromi Hirata
DOI: 10.1016/j.isci.2026.114760
Cited by: 2
References: 54

Abstract

larvae, suggesting malnutrition. Notably, excess feeding partially improved their survival. These findings reveal early pathological features in the zebrafish model of Werner syndrome.

Fields of Study & Subjects

Erythrocyte Function and Pathophysiology Mitochondrial Function and Pathology DNA Repair Mechanisms

Publication details

Journal / source
iScience
Publisher
Elsevier BV
Volume
29
Issue
3
Pages
114760–114760
Publication date
22 January 2026
Language
EN