Alox15 via H2O2 mediates TP receptor palmitoylation and its membrane trafficking leading to platelet activation

iScience 2026 Open access

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Authors: Suresh Govatati, Chandra Sekhar Yadavalli, Abhinav Sunkara, Gadiparthi N. Rao
DOI: 10.1016/j.isci.2026.114796
Cited by: 1
References: 82

Abstract

-TXA2-induced PKCθ activation, TP receptor palmitoylation, and its membrane trafficking leading to platelet activation and hemostasis.

Fields of Study & Subjects

Platelet Disorders and Treatments Inflammatory mediators and NSAID effects Antiplatelet Therapy and Cardiovascular Diseases

Publication details

Journal / source
iScience
Publisher
Elsevier BV
Volume
29
Issue
2
Pages
114796–114796
Publication date
24 January 2026
Language
EN