Protective role of PASH-1 in CGG repeat-driven RNA and protein toxicity in FXTAS

iScience 2026 Open access

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Authors: Tsung-Yuan Hsu, Hsin‐ya Yang, Lin-Shiang Hsieh, Kuan-Yen Chen, Guang‐Yuh Chiou, Albert Y. Chen, Jay Shieh, Noëlle D. L’Étoile, Paul J. Hagerman, Bi-Tzen Juang
DOI: 10.1016/j.isci.2026.114812
Cited by: 0
References: 70

Abstract

as a model for dissecting FXTAS mechanisms and exploring therapeutic strategies.

Fields of Study & Subjects

Genetic Neurodegenerative Diseases Genetics and Neurodevelopmental Disorders Amyotrophic Lateral Sclerosis Research

Publication details

Journal / source
iScience
Volume
29
Issue
2
Pages
114812–114812
Publication date
28 January 2026
Language
EN