The serotonin receptor 2b (5-HT2B) modulates heart remodeling following myocardial infarction via regulation of Hippo pathway

iScience 2026 Open access

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Authors: Ryan Potter, Min Zi, Sukhpal Prehar, Tara McNulty, Dowan Kwon, Ellie England, Maram Almutairi, Nicholas Stafford, Ardiansah Bayu Nugroho, Efta Triastuti, Luc Maroteaux, Elizabeth J. Cartwright
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DOI: 10.1016/j.isci.2026.114825
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Abstract

as a regulator of the Hippo pathway that can be targeted to improve cardiac phenotype following MI.

Fields of Study & Subjects

Cardiac Fibrosis and Remodeling Hippo pathway signaling and YAP/TAZ Congenital heart defects research

Publication details

Journal / source
iScience
Volume
29
Issue
2
Pages
114825–114825
Publication date
27 January 2026
Language
EN