CAR T-cells in hematologic malignancies: Advances, challenges, and future directions

iScience 2026 Open access

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Authors: Karol J. Hernández-Idarraga, Andrea J. Arias-Rozo, Martha L. Arango-Rodríguez, Claudia Sossa, Silvia M. Becerra-Bayona
DOI: 10.1016/j.isci.2026.115213
Cited by: 2
References: 113

Abstract

CAR delivery, aim to improve efficacy and scalability. Integration of artificial intelligence and point-of-care manufacturing may further streamline production and patient selection. Continued innovation will determine the long-term impact of CAR T-cell therapy as a scalable pillar of precision hematologic oncology.

Fields of Study & Subjects

CAR-T cell therapy research Cutaneous lymphoproliferative disorders research Lymphoma Diagnosis and Treatment

Publication details

Journal / source
iScience
Publisher
Elsevier BV
Volume
29
Issue
4
Pages
115213–115213
Publication date
4 March 2026
Language
EN