Octopus sucker-inspired, Turkish gall extract-integrated microneedle patch for oral ulcer mitigation

iScience 2026 Open access

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Authors: Lin Lin, Shilin Guo, Cheng Zhao, Xiaotan Dou, Wei Han, Chuanhui Song
DOI: 10.1016/j.isci.2026.115557
Cited by: 2
References: 29

Abstract

and in rodents. Applied to oral ulcer lesions in rats, the microneedle system exhibited prolonged mucosal retention with sustained drug release, significantly accelerating epithelial regeneration. These findings establish the sucker-inspired herbal microneedle platform as a mechanochemically optimized therapeutic strategy and provide a translational framework for modernizing traditional herbal delivery.

Fields of Study & Subjects

Advancements in Transdermal Drug Delivery Advanced Drug Delivery Systems Oral microbiology and periodontitis research

Publication details

Journal / source
iScience
Publisher
Elsevier BV
Volume
29
Issue
5
Pages
115557–115557
Publication date
1 April 2026
Language
EN