Single-cell transcriptomics reveals pediatric immune responses to COVID-19 vaccination

iScience 2026 Open access

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Authors: Xiong Zhu, Jie Wang, Xiaoxia Wang, Zhaomin Feng, Li Wan, Lin Sun, 付锦, Fei Xiao, Xiaolan Huang, 贾楠, Min Chen, Juan Zhou
+2 more Yi Wang, Quanyi Wang
DOI: 10.1016/j.isci.2026.115769
Cited by: 1
References: 52

Abstract

signaling to restrain excessive cytotoxicity and orchestrate helper T cell differentiation. Together, our atlas demonstrates that pediatric immunity to inactivated vaccines is tightly orchestrated, balancing antiviral programs with regulatory mechanisms to ensure safe protection.

Fields of Study & Subjects

Immune responses and vaccinations SARS-CoV-2 and COVID-19 Research COVID-19 Clinical Research Studies

Publication details

Journal / source
iScience
Publisher
Elsevier BV
Volume
29
Issue
5
Pages
115769–115769
Publication date
15 April 2026
Language
EN