Sex Differences in Pharmacologic Optimal Medical Therapy for Ischemic Heart Disease
Abstract
BACKGROUND: Despite guideline recommendations for optimal medical therapy (OMT) for ischemic heart disease (IHD), sex disparities in pharmacologic treatment remain poorly characterized in recent years. OBJECTIVES: The objective of the study was to examine sex differences in the use and trends of guideline-recommended OMT among adults with IHD in the United States from 2011 to 2020. METHODS: We performed a serial cross-sectional analysis using nationally representative data from the 2011 to 2020 National Health and Nutrition Examination Survey. Adults aged ≥18 years with self-reported IHD were included. OMT was defined as the use of antiplatelets, statins, β-blockers, and renin-angiotensin-aldosterone system inhibitors (RAASi). We examined differences in medication use by sex and evaluated temporal trends stratified by age (
Fields of Study & Subjects
Sex and Gender in Healthcare
Acute Myocardial Infarction Research
Cardiac Imaging and Diagnostics
Publication details
- Journal / source
- JACC Advances
- Publisher
- Elsevier BV
- Volume
- 5
- Issue
- 6
- Pages
- 102691–102691
- Publication date
- 1 April 2026
- Language
- EN