Impact of Coronary Microvascular Dysfunction on Patient-Reported Symptoms After PCI

JACC Advances 2026 Open access

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Authors: Frédéric Bouisset, Kazumasa Ikeda, Takuya Mizukami, Daniel Munhoz, Jeroen Sonck, Koshiro Sakai, Hitoshi Matsuo, Hirohiko Ando, Brian Ko, Simone Biscaglia, Fernando Rivero, Antonio Maria Leone
+15 more Andy S.C. Yong, Javier Escaned, Damien Collison, Gianluca Calogero Campo, Liyew Desta, Tetsuya Amano, Toshiro Shinke, William F. Fearon, Ethan Korngold, Evald Høj Christiansen, Colin Berry, Divaka Perera, Bernard De Bruyne, Nils P. Johnson, Carlos Collet
DOI: 10.1016/j.jacadv.2026.102946
Cited by: 1
References: 20

Abstract

BACKGROUND: Coronary microvascular dysfunction (CMD) has been proposed as a mechanism underlying residual angina after percutaneous coronary intervention (PCI). OBJECTIVES: The objective of the study was to investigate the impact of CMD on symptoms in patients undergoing PCI. METHODS: Patients with hemodynamically significant coronary artery disease (CAD) (fractional flow reserve ≤0.80) were included. CAD was classified as focal or diffuse using the pull back pressure gradient (PPG) (diffuse CAD defined as PPG

Fields of Study & Subjects

Cardiac Imaging and Diagnostics Acute Myocardial Infarction Research Coronary Interventions and Diagnostics

Publication details

Journal / source
JACC Advances
Publisher
Elsevier BV
Volume
5
Issue
8
Pages
102946–102946
Publication date
13 July 2026
Language
EN