Hemodynamic Responses to Exercise and Predictors of Exercise Capacity in Mitral Stenosis

JACC Asia 2026 Open access

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Authors: Jihoon Kim, Ki Hong Choi, Jae‐Joong Kim, Jihee Son, Eun Kyoung Kim, Sung‐A Chang, Sang-Chol Lee, Seung Woo Park, Sung-Ji Park, Jeong Hoon Yang
DOI: 10.1016/j.jacasi.2026.04.040
Cited by: 1
References: 22

Abstract

BACKGROUND: is a major indication for intervention in mitral stenosis (MS), patients in this group may exhibit wide variability in exercise tolerance. OBJECTIVES: The aim of this study was to assess hemodynamic changes during exercise in patients with severe MS using exercise cardiac catheterization. METHODS: ). RESULTS: were left ventricular global longitudinal strain, stroke volume index, and MVA, as calculated by the continuity equation, but not planimetry MVA or pressure gradient. CONCLUSIONS: exhibited limited exercise tolerance compared with those with NCD. Left ventricular global longitudinal strain and resting stroke volume index emerged as key parameters associated with exercise tolerance among MS patients.

Fields of Study & Subjects

Cardiac Valve Diseases and Treatments Cardiovascular and exercise physiology Cardiovascular Function and Risk Factors

Publication details

Journal / source
JACC Asia
Publisher
Elsevier BV
Volume
6
Issue
8
Pages
1433–1443
Publication date
25 June 2026
Language
EN