Closure of Dedicated TAVR Device for Aortic Regurgitation in LVAD Patients

Severe aortic regurgitation (AR) in patients with left ventricular assist device (LVAD) causes recirculatory flow and hemodynamic compromise. Two LVAD patients with severe AR underwent transfemoral JenaValve Trilogy implantation. Both procedures achieved immediate abolition of regurgitation; however, both prostheses subsequently showed valve closure, with one case progressing to complete thrombotic sealing. Despite closed prosthetic valves, both patients demonstrated improved LVAD efficiency and absence of clinical embolic events at last available follow-up. JenaValve Trilogy implantation can provide hemodynamic benefit in high-risk LVAD patients, even when functional or thrombotic valve closure occurs. However, long-term durability and anticoagulation strategies remain to be determined.