Multicenter international cohort study of haploinsufficiency of A20 reveals novel genetic architecture and phenotypic evolution

Journal of Allergy and Clinical Immunology 2026 Open access

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Authors: Tingyan He, Jun Wang, Manuel Carpio Tumba, Shihao Wang, Youyou Luo, Jie Chen, Guomin Li, Zhou Shu, Song Zhang, Deborah L. Stone, Yanyan Huang, Qianying Lv
+88 more Wen Xiong, Jinbo Wang, Zhongxun Yu, Charlotte Vera Cuff, Elizabeth Kairis, Akuti Kethri, Atif Towheed, Kyr Goyette, Urekha Karri, Jiebiao Wang, Chen liu, Tina Romeo, Laia Alsina, Daniel L. Rosenberg, Daniel Clemente, Juan Carlos Lopez Robledillo, Zanhua Rong, Xue Zhao, Lijun Jiang, Juan Carlos Aldave-Becerra, Ana Beatriz Muñoz-Urribarri, Prasad T. Oommen, Priscilla Campbell-Stokes, Meifang Zhu, Peng Liu, Li Guo, Yiping Xu, Zihua Yu, Huajuan Tong, Xiaojian Qiu, Yazhi Zhang, Hongbo Chen, Changming Zhang, Junbin Ou, Congcong Liu, Jinxiang Liu, Yunyan Shen, Jianshe Cao, Xinping Zhang, Kangkang Yang, Ying Bao, Zhijuan Li, Jie Cao, Yuanhui Duan, Fujuan Liu, Buyun Shi, Min Sun, Li Ma, Yongxing Chen, Wei Yang, Xu Han, Shuangyue Ma, Jie Luo, Weiyue Gu, Guoliang Yu, Weina Shi, Ruiqin Zhao, Lei Sun, Wenhui Li, Yunfei An, Xuemei Tang, Xiaodong Zhao, Tongxin Han, Jing Ma, Yan Li, Yurong Piao, Fei Sun, Dongfeng Zhang, Meina Yin, Shaoling Zheng, Li Tianwang, Huizhong Niu, Li Lin, Shiyue Mei, Fang Liz Zhou, Sirui Yang, Danlu Li, Mei Yan, Huasong Zeng, Ping Zeng, Wenjie Zheng, Xiaozhong Li, Xiaolin Li, Yuling Liu, Lijuan Huang, Haiguo Yu, Zhidan Fan, Min Shen
DOI: 10.1016/j.jaci.2026.02.002
Cited by: 3
References: 41

Fields of Study & Subjects

Immunodeficiency and Autoimmune Disorders Genomics and Rare Diseases T-cell and B-cell Immunology

Publication details

Journal / source
Journal of Allergy and Clinical Immunology
Publisher
Elsevier BV
Volume
157
Issue
6
Pages
1395–1410
Publication date
13 February 2026
Language
EN